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Description
Marbofloxacin is a synthetic, bactericidal antimicrobial, belonging to the fluoroquinolone group, which acts by inhibition of DNA gyrase.
Composition
Each ml contains: 100 mg Marbofloxacin. Indications: in cattle: Therapeutic treatment of respiratory infections caused by sensitive strains of Pasteurella multocida, Mannheimia haemolytica and Histophilus somni.
Therapeutic treatment of acute mastitis caused by E. coli strains sensitive to marbofloxacin during the lactation period. In sows: Treatment of Metritis Mastitis Agalactiae Syndrome caused by bacterial strains sensitive to marbofloxacin
It has a broad-spectrum activity in vitro against a wide range of bacteria, particularly Gram-negative bacteria but also against Gram-positive bacteria.
After a single intramuscular administration in cattle at the recommended dose of 8 mg/kg, the maximum plasma concentration of marbofloxacin (Cmax) is 8 µg/ml. Binding to plasma proteins is about 30%. Marbofloxacin is eliminated slowly, predominantly in the active form in urine and feaces.
Cattle: intramuscular use: – for respiratory infections: the recommended dosage is 8 mg/kg bodyweight i.e. 2 ml/25 kg bodyweight in a single injection.
If the volume to be injected is more than 20 ml, it should be divided between two or more injection sites.
Subcutaneous use: – acute mastitis: the recommended dosage is 2 mg/kg i.e. 1 ml/50 kg bodyweight in a single daily injection, for 3 days.
Intramuscular use: the recommended dosage is 2 mg/kg i.e.1 ml/50kg bodyweight in a single daily injection by intramuscular route, for 3 days.
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